Interstitial Cystitis

Interstitial cystitis (IC) is an inflamed or irritated bladder wall. It can lead to
scarring and stiffening of the bladder. The bladder can’t hold as much urine as it
did in the past. It is a chronic disorder. IC may also be known as:

  • Painful bladder syndrome
  • Frequency-urgency-dysuria syndrome

Experts don’t know what causes
interstitial cystitis (IC). Researchers are looking at many theories to understand
causes of IC and find the best treatments.

Most people with IC find that certain foods make their symptoms worse. These include:

  • Citrus fruits
  • Tomatoes
  • Chocolate
  • Coffee
  • Potassium-rich foods
  • Alcohol
  • Caffeinated drinks
  • Spicy foods
  • Some carbonated drinks

These are the most common symptoms of interstitial cystitis (IC):

  • Frequent urination
  • Urgency with urination
  • Feelings of pressure, pain, and
    soreness around the bladder, pelvis, and the area between the anus and vagina or anus
    and scrotum (perineum)
  • Pain during sex
  • In men, discomfort or pain in the penis and scrotum
  • In women, symptoms may get worse
    around their period

Stress may also make symptoms worse, but stress does not cause symptoms.

The symptoms of IC may look like
other conditions or health problems. Always talk with a healthcare provider for a

No single test can diagnose IC. And
symptoms of IC are a lot like those of other urinary disorders. For these reasons,
variety of tests may be needed to rule out other problems. Your healthcare provider
start by reviewing your health history and doing a physical exam. Other tests may

  • Urinalysis. Lab testing of urine to look for certain cells and chemicals. This includes red and
    white blood cells, germs, or too much protein.
  • Urine culture and cytology. Collecting and checking urine for white blood cells and bacteria. Also, if present,
    what kind of bacteria there are in the urine.
  • Cystoscopy. A thin, flexible tube and
    viewing device is put in through the urethra. It examines the bladder and other parts
    of the urinary tract. This test checks for structural changes or blockages.
  • Bladder wall biopsy. Tissue samples
    are removed from the bladder (with a needle or during surgery). They are checked
    under a microscope to see if cancer or other abnormal cells are present.
  • Lab exam of prostate secretions (in men).

    This is done to look for prostate inflammation or infection.

There is no cure for IC and it can be hard to treat. Treatments are aimed at easing
symptoms, and may include:

  • Bladder enlargement. This method
    increases bladder capacity. It also interferes with pain signals being sent by the
    nerve cells in the bladder.
  • Bladder wash. The bladder is filled with a solution that is held for varying times, from a few seconds
    to 15 minutes. Then it is drained out through a catheter.
  • Medicine. Medicine may be taken by
    mouth or put right into the bladder. There are many different medicines that may be
  • Transcutaneous electrical nerve
    stimulation (TENS).
    Mild electric pulses enter the body for minutes to hours.
    This is done 2 or more times a day. The pulses are sent through wires placed on the
    lower back. Or through special devices put into the vagina in women or into the
    rectum in men. For some people, TENS eases bladder pain and urinary frequency and
  • Bladder training.  You urinate at
    certain times and use relaxation methods and distractions to help keep to the
    schedule. Over time, you try to lengthen the time between the scheduled
  • Surgery. Surgery to remove all or
    part of the bladder may be done in severe cases, if other treatments don’t work.

Management of IC may also include:

  • Diet changes. No proof links diet to
    IC, but some believe that alcohol, tomatoes, spices, chocolate, caffeinated and
    citrus drinks, and high-acid foods may contribute to bladder inflammation. Removing
    these from the diet may help to decrease some symptoms.
  • Not smoking. Many people with IC find that smoking makes their symptoms worse.
  • Exercise. Exercise may help ease symptoms or make them stop for a while.
  • Reducing stress. There is no proof
    that stress causes IC. But if a person has IC, stress can make the symptoms

Talk with a healthcare provider
about any questions of concerns you may have.

  • Interstitial cystitis (IC) is an inflamed or irritated bladder wall.
  • Experts don’t know what causes IC. It
    does not get better with antibiotics.
  • Symptoms include pain during sex and
    frequent and urgent urination. There may also be pressure, pain, and soreness around
    the bladder, pelvis, and the area between the anus and vagina (women) or the anus
    scrotum (men).
  • There is no best way to diagnose IC. A
    variety of tests may be needed. These include urine tests, imaging tests, and biopsy.

  • Treatments are aimed at easing symptoms. A variety of procedures, medicines, and lifestyle
    changes may be advised.

Tips to help you get the most from a visit to your healthcare provider:

  • Know the reason for your visit and what you want to happen.
  • Before your visit, write down questions you want answered.
  • Bring someone with you to help you ask questions and remember what your provider tells
  • At the visit, write down the name of a new diagnosis, and any new medicines, treatments,
    or tests. Also write down any new instructions your provider gives you.
  • Know why a new medicine or treatment is prescribed, and how it will help you. Also
    know what the side effects are.
  • Ask if your condition can be treated in other ways.
  • Know why a test or procedure is recommended and what the results could mean.
  • Know what to expect if you do not take the medicine or have the test or procedure.
  • If you have a follow-up appointment, write down the date, time, and purpose for that
  • Know how you can contact your provider if you have questions.