AFLP is a rare, but serious, liver problem in pregnancy. With AFLP the liver cells
have too much fat, which can damage the liver.
Healthcare providers don’t know the exact cause of AFLP. Fats called triglycerides
and fatty acids are normally broken down in the liver. But with AFLP your body makes
too much of these. Research shows that AFLP may be an inherited problem with how the
liver breaks down fats.
AFLP is rare, but it is more likely if you are:
- Having your first pregnancy
- Pregnant with twins or more
- Pregnant with a boy
There is a chance that AFLP can happen again with a future pregnancy.
AFLP usually starts late in the third trimester of pregnancy. These are the most common
symptoms of AFLP:
- Nausea and vomiting
- Belly pain, especially in the top right side
- Feeling unwell (malaise)
- Yellowing of skin, eyes, and mucous membranes (jaundice)
The symptoms of AFLP may look
like other health conditions. Always see your healthcare provider for a diagnosis.
To diagnose AFLP, your healthcare
provider will review your health history and do a physical exam. The best way
to diagnose AFLP is by a liver biopsy. This involves taking a sample of liver tissue
exam under a microscope. It may not always be possible in pregnancy. Most often, your
symptoms of AFLP are enough to diagnose the condition. Blood tests can check for other
conditions that have similar symptoms. Other tests that may be used include:
Ultrasound. This test uses sound waves and a computer to make images
of blood vessels, tissues, and organs.
images of the body.
Once AFLP is diagnosed, your baby is delivered as quickly as possible. This can help
lower the risks to you and your baby. You may need to be in intensive care for several
days after delivery. In most cases, your liver function returns to normal within a
Both you and your developing baby can become very sick if AFLP is not treated. You
can have liver failure, severe bleeding, kidney failure, and severe infection. These
can be life-threatening for both you and your baby. Getting an early diagnosis and
treatment is important.
AFLP is a serious condition that
can’t be predicted or prevented.
- AFLP is a rare but serious liver problem in which there is too much fat in the liver
or liver cells.
- Healthcare providers don’t know the exact cause of AFLP.
- AFLP is more common in first pregnancies.
- A liver biopsy is the best way to diagnose AFLP.
- Once the condition is diagnosed, the baby is delivered as quickly as possible to lower the
risks to mother and baby.
Tips to help you get the most from a visit to your healthcare provider:
- Know the reason for your visit and what you want to happen.
- Before your visit, write down questions you want answered.
- Bring someone with you to help you ask questions and remember what your provider tells
- At the visit, write down the name of a
new diagnosis and any new medicines, treatments, or tests. Also write down any new
instructions your provider gives you.
- Know why a new medicine or treatment
is prescribed and how it will help you. Also know what the side effects are.
- Ask if your condition can be treated in other ways.
- Know why a test or procedure is recommended and what the results could mean.
- Know what to expect if you do not take the medicine or have the test or procedure.
- If you have a follow-up appointment, write down the date, time, and purpose for that
- Know how you can contact your provider if you have questions.