Fibroids are firm, dense tumors
made of smooth muscle cells and fibrous connective tissue. They develop in the uterus.
About 1 in 5 to 1 in 2 women of reproductive age have fibroids, but not all are
diagnosed. Fibroids are very common. Only about one-third of these fibroids are large
enough to be found by a healthcare provider during a physical exam.
In almost all fibroid cases, the
tumors are not cancer. These tumors are not linked to cancer and don’t increase a
woman’s risk for uterine cancer. They may be as small as a pea to as large as a softball
or small grapefruit.
Experts don’t know what causes
uterine fibroids. It may be that each tumor develops from an abnormal muscle cell
uterus. This cell multiplies rapidly because of the effect of estrogen.
Women who are nearing menopause are
at the greatest risk for fibroids. This is because of their long exposure to high
of estrogen. Women who are obese and of African-American background also seem to be
higher risk. The reasons for this are not clearly understood.
Other risk factors:
- Diet high in red meat
- Family history of fibroids
- High blood pressure
Some women who have fibroids have
no symptoms. Or they have only mild symptoms. Other women have more severe symptoms.
These are the most common symptoms for uterine fibroids:
- Heavy or lengthy periods
- Abnormal bleeding between periods
- Pelvic pain. This happens as the tumor
presses on pelvic organs
- Frequent urination
- Low back pain
- Pain during intercourse
- A firm mass often near the middle of
the pelvis. This can be felt by your healthcare provider.
Fibroids are most often found
during a routine pelvic exam. Your healthcare provider may feel a firm, irregular
mass during an abdominal or pelvic exam. You may need other tests. These include:
X-ray. Beams of energy make images of
bones and internal organs on film.
Transvaginal ultrasound. This is an
ultrasound test using a small tool (transducer) that is placed in the vagina.
MRI. This test uses a large magnet,
radio waves, and a computer to make 2-D images of an internal organ or
Hysterosalpingography. This is an
X-ray exam of the uterus and fallopian tubes that uses dye. It’s often done to rule
out blocked fallopian tubes.
Hysteroscopy. For this test, the
healthcare provider uses a viewing tool (hysteroscope) to look at the canal of the
cervix and the inside of the uterus. The tool is inserted through the vagina.
Endometrial biopsy. For this
procedure, the healthcare provider takes a sample of tissue through a tube inserted
into the uterus.
Blood test. This is to check for
iron-deficiency anemia if the fibroid causes heavy bleeding
Most fibroids stop growing or may
even shrink as you get near menopause. Your healthcare provider may suggest “watchful
waiting.” With this approach, your healthcare provider monitors your symptoms carefully
to make sure you have no significant changes. He or she will check that the fibroids
If your fibroids are large or cause
a lot of symptoms, you may need treatment. Treatment will depend on your age and if
want to get pregnant in the future.
In general, treatment for fibroids
Hysterectomy. This is the surgical
removal of the entire uterus. Fibroids are the main reason for hysterectomies in the
Conservative surgical therapy.
myomectomy. With this approach, fibroids are removed, but
the uterus stays intact. This may allow a future pregnancy.
Gonadotropin-releasing hormone agonists
This approach lowers your estrogen level. This triggers a
“medical menopause.” Sometimes GnRH agonists are used to shrink the fibroid to make
Anti-hormonal medicines. Certain
medicines such as progestin block estrogen and seem to work to treat fibroids.
Anti-progestins block the action of progesterone. They are also sometimes used.
Uterine artery embolization. This is
also called uterine fibroid embolization. The healthcare provider finds the arteries
supplying blood to the fibroids. Then the provider blocks them off (embolizes them).
This cuts off the blood supply to the fibroids and shrinks them. Healthcare
providers are studying the long-term effects of this procedure on fertility and
regrowth of the fibroid tissue.
This procedure uses sound waves to shrink the fibroids through
the guidance of MRI.
needle is inserted into the fibroids, usually guided by laparoscopy, and electric
current or freezing is used to destroy the fibroids.
Anti-inflammatory painkillers. This
type of medicine often works well for women who have occasional pelvic pain or
Hormonal therapy to reduce
Tanexamic acid to reduce
In some cases, heavy or lengthy
periods, or abnormal bleeding between periods can lead to iron-deficiency anemia.
will need treatment for this.
Uterine fibroids may affect the
reproductive system. They can cause infertility, increased risk for miscarriage, or
problems during pregnancy.
- Uterine fibroids are firm, dense
tumors that are made of smooth muscle cells and fibrous connective tissue that
develop in the uterus.
- Fibroids are not cancer and don’t
increase a woman’s risk for uterine cancer.
- Women who are nearing menopause are at
the greatest risk for fibroids. This is because of their long exposure to high levels
- Symptoms may include heavy and
prolonged periods, bleeding between periods, and pelvic pain.
- Fibroids are most often found during a
routine pelvic exam.
- If treatment is needed, it may include
medicines or surgery.
Tips to help you get the most from
a visit to your healthcare provider:
- Know the reason for your visit and
what you want to happen.
- Before your visit, write down
questions you want answered.
- Bring someone with you to help you ask
questions and remember what your provider tells you.
- At the visit, write down the name of a
new diagnosis, and any new medicines, treatments, or tests. Also write down any new
instructions your provider gives you.
- Know why a new medicine or treatment
is prescribed, and how it will help you. Also know what the side effects are.
- Ask if your condition can be treated
in other ways.
- Know why a test or procedure is
recommended and what the results could mean.
- Know what to expect if you do not take
the medicine or have the test or procedure.
- If you have a follow-up appointment,
write down the date, time, and purpose for that visit.
- Know how you can contact your provider
if you have questions.